Tag Archives: decitabine

The foetal haemoglobin story just got more complicated

Many of us think that foetal haemoglobin (Hb F) is the key to a “cure” for sickle cell disease. The genes that make Hb F are switched off shortly after we are born and then remain inactive throughout the rest … Continue reading

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Update on clinical trials in sickle cell disease

MST-188 Otherwise known as Purified Poloxamer 188, is a designated orphan drug by the US Food and Drug Administration (FDA) for trial in sickle cell disease. It is a synthetic co-polymer of polyoxyethylene (POE) and polyoxypropylene (POP) and is thought … Continue reading

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