Tag Archives: acute chest syndrome

Hydroxycarbamide and “silent cerebral infarcts”

The first reports dating from 1995 showed that taking hydroxycarbamide regularly reduced the frequency of painful crises and of the acute chest syndrome and also reduced the need for blood transfusion. This breakthrough has since been followed by numerous reports … Continue reading

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Poloxamer 188 – helpful during a painful crisis or not?

Research involving Poloxamer 188 (also know as RheothRx or MST 188) continues to appear in the journals. The latest is some interesting work from a team working in Hungary and France published in the British Journal of Haematology (1). Poloxamer … Continue reading

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Asthma and sickle cell disease

In celebration of World Sickle Cell Day on June 19th The Lancet has published a series of specially commissioned articles on controversial topics in sickle cell. The first, written by Michael DeBaun, from Vanderbilt University, Nashville and Robert Strunk, from … Continue reading

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The lungs and sickle cell

For most people a painful crisis is the usual problem in sickle cell. Crises occur again and again and are the most frequent reason for admission to hospital. The underlying reason for a painful crisis is blockage of small blood … Continue reading

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